“Above all, be at ease, be as natural and spacious as possible. Slip quietly out of the noose of your habitual anxious self, release all grasping, and relax into your true nature.”—Songyal Rinponche (via new-ancient)
“Our revenge is the sweetest, bitch cause I’m coming
Gonna die in my arms, for what you did to my mother (my mama!)
Hundred dead bitches, (Lord) hundred black coffins (why?)
12 gauge, shotgun, chest full of carbon (boom-boom)”—Rick Muthaphukin Ross
“One thing is certain: the arts keep you alive. They stimulate, encourage, challenge, and, most of all, guarantee a future free from boredom. They allow growth and even demand it in that time of life we call maturity but too often enter it with a childish faith that what we learned in youth is sustenance enough for the years when most men are mentally famished but won’t admit it—or when they are apt to curb their hunger with the sops of complacency, security, and the assurance of death.”—Vincent Price
“Toxic masculinity hurts men, but there’s a big difference between women dealing with the constant threat of being raped, beaten, and killed by the men in their lives, and men not being able to cry.”—Robert Jensen (via blondeyed)
“I think people need housing. And there’s empty buildings, I think people should live in there. If you want to call them squatters, trespassers, hey, I call Wall Street thieves!”—Al Lewis - aka Grandpa Munster
Reverse-engineered life form could be used to test drugs.
A jellyfish made of silicone and rat heart cells ‘swims’ in water when subjected to an electric field. Image: Harvard University/Caltech
Bioengineers have made an artificial jellyfish using silicone and muscle cells from a rat’s heart. The synthetic creature, dubbed a medusoid, looks like a flower with eight petals. When placed in an electric field, it pulses and swims exactly like its living counterpart.
“Morphologically, we’ve built a jellyfish. Functionally, we’ve built a jellyfish. Genetically, this thing is a rat,” says Kit Parker, a biophysicist at Harvard University in Cambridge, Massachusetts, who led the work. The project is described today in Nature Biotechnology.
Parker’s lab works on creating artificial models of human heart tissues for regenerating organs and testing drugs, and the team built the medusoid as a way of understanding the “fundamental laws of muscular pumps”. It is an engineer’s approach to basic science: prove that you have identified the right principles by building something with them.
In 2007, Parker was searching for new ways of studying muscular pumps when he visited the New England Aquarium in Boston, Massachusetts. “I saw the jellyfish display and it hit me like a thunderbolt,” he says. “I thought: I know I can build that.” To do so, he recruited John Dabiri, a bioengineer who studies biological propulsion at the California Institute of Technology (Caltech) in Pasadena. “I grabbed him and said, ‘John, I think I can build a jellyfish.’ He didn’t know who I was, but I was pretty excited and waving my arms, and I think he was afraid to say no.”
Janna Nawroth, a graduate student at Caltech who performed most of the experiments, began by mapping every cell in the bodies of juvenile moon jellies (Aurelia aurita) to understand how they swim. A moon jelly’s bell consists of a single layer of muscle, with fibres that are tightly aligned around a central ring and along eight spokes.
To make the bell beat downwards, electrical signals spread through the muscle in a smooth wave, “like when you drop a pebble in water”, says Parker. “It’s exactly like what you see in the heart. My bet is that to get a muscular pump, the electrical activity has got to spread as a wavefront.”